The most dramatic complication of HCM is sudden cardiac death, with the highest incidence in younger patients. Ventricular fibrillation is the cause of sudden cardiac death in > 80% of cases. Risk stratification strategies are used to identify patients' risk for sudden cardiac death and patients who would benefit from implantable cardioverter defibrillator implantation. A maximal left ventricular wall thickness of ≥ 30 mm on echocardiogram is an established risk factor for sudden cardiac death.
Abnormal electrocardiogram findings may be the first manifestations in patients with HCM and may aid in differentiation of HCM from other pathological conditions. However, studies have demonstrated that EKG findings do not reliably correlate with severity of disease.
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Cite this: Jamshid Shirani. Fast Five Quiz: Hypertrophic Cardiomyopathy Workup - Medscape - Apr 13, 2022.