Hypertrophic cardiomyopathy (HCM) is a genetic disease of the heart characterized by an increase in left ventricular wall thickness (≥ 15 mm) in the absence of abnormal loading conditions (hypertension, congenital heart disease, or valvular disease) or other inherited or acquired diseases capable of producing such degree of hypertrophy. Mutations in genes encoding cardiac sarcomere proteins are present in up to 60% of adolescent and adults. Clinical presentation varies from shortness of breath to sudden cardiac death.
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Cite this: Jamshid Shirani. Fast Five Quiz: Hypertrophic Cardiomyopathy Workup - Medscape - Apr 13, 2022.