Fast Five Quiz: Gastroesophageal Reflux Disease (GERD)

B.S. Anand, MD


July 29, 2021

Studies have shown that GERD is highly prevalent in patients who are morbidly obese and that a high body mass index (BMI) is a risk factor for the development of this condition. The hypothesis that obesity increases esophageal acid exposure is supported by the documentation of a dose-response relationship between increased BMI and increased prevalence of GERD and its complications.

In addition, other risk factors associated with the development of GERD include the following:

  • Age ≥ 50 years

  • Nicotine or tobacco use

  • Alcohol consumption

  • Connective tissue disorders

  • Pregnancy

  • Postprandial supination

In addition, certain drugs have been associated with the development of GERD, including the following:

  • Albuterol

  • Anticholinergics

  • Antidepressants

  • Aspirin

  • Benzodiazepines

  • Calcium-channel blockers

  • Glucagon

  • Nitroglycerin

  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

Read more on the etiology of GERD.


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