Fast Five Quiz: Testicular Cancer

Elwyn C. Cabebe, MD


June 15, 2021

According to NCCN guidelines, radical inguinal orchiectomy is recommended as the primary treatment for most patients with a testicular mass concerning for malignancy on ultrasonography. In patients with ambiguous abnormality that might be malignant on ultrasonography, an open inguinal biopsy (testis-sparing surgery or partial orchiectomy) with intraoperative frozen section analysis may be performed; however, such cases are extremely rare. NCCN guidelines state that an open inguinal biopsy of the contralateral testis can be considered if an ambiguous suspicious mass is identified on ultrasound or if the testis is cryptorchid or shows marked atrophy. However, biopsies are not recommended for microcalcifications.

The NCCN recommends that sperm banking be discussed with patients of reproductive age before undergoing any therapeutic intervention that may compromise fertility. It can be performed before orchiectomy in patients with risk factors for infertility, including atrophic contralateral testicle.

Read more about the treatment of testicular cancer.

This Fast Five Quiz was excerpted and adapted from the Medscape Drugs & Diseases article Testicular Cancer.

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