Fast Five Quiz: Myasthenia Gravis Workup

Richard Nowak, MD, MS


July 08, 2021

Several provocative maneuvers that fatigue specific muscle groups are useful in diagnosing MG, such as having the patient perform deep knee bends with the back straight and their palm held on the palm of the examiner. An increase in pressure against the examiner's palm while doing this maneuver is an early sign of weakness. Also, the repeated rising from a chair without using the arms may cause an exaggerated lean-forward and ''buttocks-first'' maneuver. To examine possible ocular signs of MG, a sustained upgaze (60-180 seconds) may reveal fatigable ptosis in one or both eyes.

Learn more about the physical examination of patients with suspected MG.


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