Fast Five Quiz: Autosomal Dominant Polycystic Kidney Disease Presentation and Diagnosis

Neera K. Dahl, MD, PhD

Disclosures

June 29, 2021

Figure 1. Colored MRI of the abdomen of a 33-year-old woman with polycystic kidneys (red). The front of the body is at the top of the image. The majority of the tissue of the kidneys has been replaced by cysts (dark red).

Pain in the abdomen, flank, or back is almost universally present in patients with ADPKD and is the most common initial sign. Any of the following can be responsible for the pain:

Symptoms related to renal failure (eg, pallor, uremic fetor, dry skin, edema) are unusual upon presentation.

Patients with early-stage ADPKD may also report fatigue, breathlessness, weakness, and malaise.

Learn more about the presentation of ADPKD.

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