Myelodysplastic syndrome (MDS) is a group of related disorders that arise as the result of distorted hematopoietic stem cell function, inflammatory and innate immune deregulation, and multiple genomic events. These molecular alterations increase the risk of infections, bleeding, and potentially, progression to acute myeloid leukemia (AML). The disease course involves a series of cytogenetic events, making the condition a heterogeneous one. MDS may involve one, two, or three myeloid hematopoiesis cell lineages — erythrocytic, granulocytic, and/or megakaryocytic — depending on the subtype and stage of the disease.
Would you be able to identify one of these heterogeneous disorders? Test your knowledge with this quick quiz.
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Cite this: Emmanuel C. Besa. Fast Five Quiz: Myelodysplastic Syndrome Presentation and Diagnosis - Medscape - May 12, 2021.