In patients with elevated triglycerides (200-499 mg/dL) or very high triglycerides (≥ 500 mg/dL), the AHA has recommended 2-4 g/d of EPA alone or EPA plus DHA. The AHA has concluded that prescription omega-3 fatty acids at a dose of 4 g/d are an effective and safe option for reducing triglycerides as monotherapy or as an adjunct to other lipid-lowering agents. Use for improving atherosclerotic cardiovascular disease risk in patients with hypertriglyceridemia is supported by a 25% reduction in major adverse cardiovascular events in REDUCE-IT, a randomized placebo-controlled trial of EPA only (ie, icosapent) in high-risk patients treated with a statin.
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Cite this: Mary L. Windle. Fast Five Quiz: Omega-3 Fatty Acids (Fish Oil) - Medscape - Apr 09, 2021.