Fast Five Quiz: Chronic Kidney Disease (CKD) Hyperphosphatemia

A. Brent Alper, Jr, MD, MPH


April 26, 2021

The results from a full chemistry profile can help determine the causes of hyperphosphatemia. Low serum calcium levels along with high phosphate levels are observed with renal failure, hypoparathyroidism, and pseudohypoparathyroidism. Blood urea nitrogen (BUN) and creatinine values can also help to determine whether renal failure is the cause of hyperphosphatemia.

Relatively low levels of intact PTH along with normal renal function can be found in patients with primary or acquired hypoparathyroidism. High serum calcium and increased phosphate levels are observed with vitamin D intoxication and milk-alkali syndrome. Low levels of PTH and vitamin D are seen in milk-alkali syndrome.

Learn more about the workup and diagnosis of hyperphosphatemia.


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