Two major groups of asthma phenotypes have been identified on the basis of the involved inflammatory pathway: the Th2-high and Th2-low phenotypes. Severe obesity-related asthma is considered a Th2-low phenotype, as is neutrophilic asthma. Early-onset allergic asthma and late-onset eosinophilic asthma are associated with Th2-high–related inflammation.
Learn more about the role of inflammation in severe asthma.
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Cite this: Zab Mosenifar. Fast Five Quiz: Severe Asthma Phenotypes - Medscape - Apr 05, 2021.