The prevalence of AERD is highest among patients with severe asthma. In AERD, patients have both nasal polyps and sinusitis with an allergic reaction involving both the upper and lower respiratory tracts after ingesting or inhaling aspirin or any other nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase-1.
AERD is distinct from the usual characteristics of the allergic asthma phenotype in that it is more common in women, rarely clusters in families, and typically develops in the third decade of life.
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Cite this: Zab Mosenifar. Fast Five Quiz: Severe Asthma Phenotypes - Medscape - Apr 05, 2021.