Normal bowel function necessitates coordinated motility, mucosal transport, and defecation reflexes. Opioids impede these processes throughout the entire gastrointestinal system. Opioid-induced constipation specifically results from disordered anal sphincter function, impaired propulsive peristalsis, and inhibition of intestinal mucosal secretion.
Learn more about the pathophysiology of constipation.
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Cite this: B.S. Anand. Fast Five Quiz: Opioid-Induced Constipation - Medscape - Oct 15, 2020.