Fast Five Quiz: Rheumatoid Arthritis Workup

Herbert S. Diamond, MD


June 10, 2020

In this case scenario, based on the patient's history and laboratory findings, it would be appropriate to include arthrocentesis and synovial fluid analysis in the initial workup for RA to rule out gout, pseudogout, and septic arthritis.

As with RA, MRI is not a routine imaging modality for patients with crystalline arthropathy or infectious arthritis. It is, however, useful in the workup of patients with septic arthritis.

Although ultrasonography may provide rapid visualization of the joint, it will not consistently distinguish RA from crystalline arthropathy or septic arthritis.

Repeat RF testing may be considered; however, 1%-5% of healthy patients have a seropositive test result for RF, and this is insufficient for a diagnosis of RA. Therefore, the result of a repeat test would neither confirm RA nor rule out an alternative diagnosis.

Learn more about diagnostic considerations in patients with RA.

Editor's Recommendations


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.