In patients with progressive renal disease, protein restriction of as much as 0.8-1 g/kg/day may hinder the progression of nephropathy. When patients have advanced nephropathy, phosphate binders should also be utilized to restrict phosphorus and potassium.
A recent retrospective study found that, compared with kidney transplantation alone, simultaneous pancreas-kidney transplantation was associated with a nearly two-fold lower 10-year mortality rate among patients with T1DM. Combined transplantation may also improve quality of life and halt or reverse diabetic complications.
Insulin requirements are often reduced with dialysis treatment, which partially reverses insulin resistance.
Kidney function may be improved by the reduction of serum urate levels.
Learn more about options for the management of advanced diabetic nephropathy.
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Cite this: A. Brent Alper. Fast Five Quiz: Diabetic Nephropathy Management - Medscape - Apr 24, 2020.