Fast Five Quiz: Diabetic Nephropathy Management

A. Brent Alper, Jr, MD, MPH


April 24, 2020

In patients with progressive renal disease, protein restriction of as much as 0.8-1 g/kg/day may hinder the progression of nephropathy. When patients have advanced nephropathy, phosphate binders should also be utilized to restrict phosphorus and potassium.

A recent retrospective study found that, compared with kidney transplantation alone, simultaneous pancreas-kidney transplantation was associated with a nearly two-fold lower 10-year mortality rate among patients with T1DM. Combined transplantation may also improve quality of life and halt or reverse diabetic complications.

Insulin requirements are often reduced with dialysis treatment, which partially reverses insulin resistance.

Kidney function may be improved by the reduction of serum urate levels.

Learn more about options for the management of advanced diabetic nephropathy.

Editor's Recommendations


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.