It is very important to be able to distinguish sickle beta+ thalassemia from sickle trait. In the former, the amount of Hgb S is greater than the amount of Hgb A. In the latter, there is more Hgb A than Hgb S. People with sickle beta+ thalassemia have manifestations of sickle cell disease.
Learn more about diagnostic considerations in SCD.
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Cite this: Sophie M. Lanzkron. Fast Five Quiz: Sickle Cell Disease Presentation and Diagnosis - Medscape - Sep 24, 2021.