Fast Five Quiz: Advanced and Metastatic Prostate Cancer Treatment

Daniel S. Schwartz, MD, MBA


May 02, 2022

Despite advances in care, most men with metastatic prostate cancer will ultimately experience disease progression. In these cases, integrative palliative care is important. Transurethral resection and cauterization may be used as initial treatment for prostatic bleeding. If these methods are unsuccessful, medications can be tried, including ADT if it is not already being used. If ADT is not already being used, aminocaproic acid and megestrol may help some patients.

Placement of a urinary sphincter may be beneficial for patients with incontinence secondary to radical prostatectomy or RT. Rarely, urinary diversion may be considered as a last-resort treatment.

The management of bone pain due to metastatic disease is a multifaceted endeavor that requires narcotics, awareness of fractures, and possibly but not preferably, palliative RT.

The combination of mitoxantrone and prednisone may treat the symptoms of metastatic disease, but it has no impact on survival.

Learn more about palliative care for metastatic prostate cancer.


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