The Gleason grading system is currently the most common classification used that helps to determine the histologic characteristics of prostate cancer. Patients with a Gleason score of 6 or higher have prostate cancer that is likely to progress to advanced cancer if it hasn't already. A PSA level of ≥ 10 ng/mL also points to the likelihood of disease progression.
Learn more about the diagnosis and staging of advanced prostate cancer.
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Cite this: Daniel S. Schwartz. Fast Five Quiz: Advanced and Metastatic Prostate Cancer Presentation and Diagnosis - Medscape - Jun 27, 2022.