Fast Five Quiz: Advanced and Metastatic Prostate Cancer

Daniel S. Schwartz, MD, MBA

Disclosures

December 30, 2019

Immediate bilateral orchiectomy is indicated when spinal cord compression is present because it avoids the possibility of a flare response that can occur during the first 3 weeks of treatment with a luteinizing hormone-releasing hormone (LHRH) agonist.

The appropriate treatment initiation algorithm following biochemical recurrence is controversial. Factors to consider include the type of local therapy (if any) previously used, the patient's life expectancy, the likelihood of cure, the risk for increased morbidity, and the patient's quality of life. Therapeutic options include LHRH agonists, LHRH antagonists, complete androgen blockade, nonsteroidal antiandrogen monotherapy, or bilateral orchiectomy.

Early salvage radiation therapy may reduce the overtreatment associated with adjuvant radiation therapy without compromising disease control in patients with advanced or metastatic prostate cancer.

Learn more about the management of advanced and metastatic prostate cancer.

Access the NICE Guidance – Prostate Cancer: Diagnosis and Management and Cancer of the Prostate: ESMO Clinical Practice Guidelines for recommendations for prostate cancer screening, diagnosis, and therapeutic strategies.

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