Fast Five Quiz: Severe Psoriasis

Dirk M. Elston, MD; William D. James, MD


December 20, 2021

Psoriasis is independently associated with increased mortality. Moreover, men with severe psoriasis died 3.5 years earlier than men without the disease. Likewise, women with severe psoriasis died 4.4 years earlier than women without the disease.

This increase in mortality is due partially to the increased prevalence of cardiovascular, infectious, and neoplastic disorders found in psoriasis patients. Patients with more extensive psoriatic skin disease are at greater risk for major medical comorbidities, including heart and blood vessel disease, chronic lung disease, diabetes, kidney disease, joint problems, and other health conditions. Overall, the risk for any other type of serious illness was 35% higher for those with severe psoriasis.

Severe psoriasis can occur in individuals younger than 25 years.

Learn more about the epidemiology for severe psoriasis.


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