Nonspecific pain is the key presenting symptom of metastatic bone disease. Another characteristic is pain at rest and during the night. This is often seen in patients older than 50 years with metastatic bone disease. Localized pain, worsening of primary cancer–related symptoms, and pain only on activity are not key presenting symptoms of metastatic bone disease. It should also be noted that osteomyelitis and Paget disease display manifestations of nonspecific pain similar to those seen in metastatic bone disease.
See more information about the presentation of metastatic bone disease here.
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Cite this: Maurie Markman. Fast Five Quiz: How Much Do You Know About Metastatic Bone Disease? - Medscape - May 20, 2019.
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