Fast Five Quiz: Alzheimer's Disease Differential Diagnosis and Workup

Jasvinder P. Chawla, MD, MBA

February 22, 2022

Genotyping for APOE alleles is a research tool that has been helpful in determining the risk for Alzheimer's disease in patient populations, but until recently it was of little, if any, value in making a clinical diagnosis and developing a management plan in individual patients. The APOE genotypes with highest risks for Alzheimer's disease were ε43 and ε44, whereas those with the lowest risks were ε22, ε32, ε42, and ε33.

The CFTR gene is associated with cystic fibrosis. The BRCA1 gene is associated with increased risk for breast and ovarian cancer.

The PARK7 gene (also known as DJ-1) is associated with early-onset Parkinson's disease.

Learn more about genetic testing for Alzheimer's disease.

Editor's Recommendations

1 2 3 4 5 6

Next Section

Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.

Cite this: Jasvinder P. Chawla. Fast Five Quiz: Alzheimer's Disease Differential Diagnosis and Workup - Medscape - Feb 22, 2022.

Comments

Commenting is limited to medical professionals. To comment please Log-in.

Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.