Fast Five Quiz: Metastatic Breast Cancer Signs and Symptoms

Elwyn C. Cabebe, MD; Winston W. Tan, MD, FACP


December 15, 2021

As with breast cancer metastases to other sites, liver metastases may or may not produce symptoms. Commonly reported symptoms include:

  • Itching: The itching associated with liver metastases is caused by bile acid build up in the skin. This itching may be severe and is commonly reported as one of the more annoying symptoms.

  • Jaundice: The skin or eyes may become yellowed because of extensive liver involvement or blockage of the bile duct.

  • Abdominal pain: This is typically felt under the ribs on the right side.

  • Shoulder pain: Nerves that travel near the diaphragm may become compressed and cause pain in the right shoulder.

  • Hiccups: An enlarged liver may press against the diaphragm and cause hiccups.

  • Nausea, loss of appetite, and weight loss

  • Fatigue

  • Fever

  • Ascites

  • Swelling of the ankles

Learn more about metastatic breast cancer.


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