Fast Five Quiz: Metastatic Breast Cancer Signs and Symptoms

Elwyn C. Cabebe, MD; Winston W. Tan, MD, FACP


December 15, 2021

Primary breast cancer cells metastasize through the blood vessels to distant organs. Patients frequently develop metastases at multiple sites. The most common sites for metastatic spread of breast cancer are bone, lung, and liver. In a study of autopsies, the following sites were noted, in decreasing order of frequency:

  • Lung

  • Bone

  • Liver

  • Pleura

  • Adrenal glands

  • Gastrointestinal

  • Peritoneum

  • Pericardium

  • Brain

  • Skin

  • Ovary

  • Kidney

  • Thyroid

  • Pancreas

  • Spleen

  • Heart

  • Uterus

Learn more about metastatic breast cancer.


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