The ADA, WHO and IDF use varying thresholds and criteria for assessing prediabetes, including differences in IFG thresholds and the utility of the A1c test. With a range of criteria available for prediabetes identification, populations with prediabetes identified by each method vary widely and have limited overlap. The ADA threshold for IFG is 5.6-6.9 mmol/L (100-125 mg/dL), whereas the WHO uses a higher range of 6.1-6.9 mmol/L (110-125 mg/dL).
Unlike the ADA, the WHO does not endorse the use of the A1c test to screen for prediabetes. The availability of A1c testing may be limited in developing countries and may explain this decision. However, the A1c test is considered by many experts as a more reliable test of impaired glucose homeostasis because it is reflective of steady-state blood glucose levels over a period of several months; therefore, it is not prone to the day-to-day variability that may confound assessment of IGT or IFG.
Medscape © 2019 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Anne L. Peters. Fast Five Quiz: Prediabetes - Medscape - Oct 03, 2019.