
Chemoradiotherapy (CRT) or stereotactic body radiotherapy (SBRT) may be offered to patients with local progression but no metastases, provided they have a performance status of 2 or less and a favorable comorbidity profile.
CRT or SBRT may be offered to patients who have responded to an initial 6 months of chemotherapy or have stable disease, have developed unacceptable chemotherapy-related toxicities, or have a decline in performance status as a consequences of chemotherapy toxicity. If patients respond or their disease has at least stabilized after 6 months of induction chemotherapy, CRT or SBRT may be offered as an alternative to continuing chemotherapy alone. SBRT may be offered even though evidence supporting SBRT is not robust.
For more information on CRT and SBRT in locally advanced pancreatic cancer, read here and here.
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Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Michael J. Pishvaian. Fast Five Quiz: Test Your Knowledge of the Diagnosis and Treatment of Locally Advanced, Unresectable Pancreatic Cancer - Medscape - Sep 26, 2018.
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