Indicators of poor prognosis during acute episodes include the following:
Initial temperature measurement higher than 106°F or a temperature higher than 108°F or a temperature persisting above 102°F despite aggressive cooling measures
Coma duration longer than 2 hours
Severe pulmonary edema
Delayed or prolonged hypotension
Lactic acidosis in patients with classic heat stroke
Acute kidney injury and hyperkalemia
Aminotransferase levels greater > 1000 IU/L during the first 24 hours
Morbidity and mortality from heat stroke are related to the duration of the temperature elevation. When therapy is delayed, the mortality rate may be as high as 80%; however, with early diagnosis and immediate cooling, the mortality rate can be reduced to 10%. Mortality is highest among elderly persons, patients with preexisting disease, those confined to bed, and those who are socially isolated.
For more on the prognosis of heat stroke, read here.
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Cite this: Fast Five Quiz: Are You Familiar With Key Elements Regarding Heat Stroke? - Medscape - Aug 02, 2017.