Fast Five Quiz: What Do You Know About Food Allergies?

Scott H. Sicherer, MD


November 11, 2016

In cases of allergic eosinophilic esophagitis, a biopsy may need to be performed. Elimination diets with gradual reintroduction of foods and supervised oral food challenges are often needed to help identify the causative foods.

Simple tests for food-specific IgE antibodies are available, but the clinician must appreciate that a positive test for food-specific IgE primarily denotes sensitization and may not confirm clinical allergy. A physician-supervised oral food challenge may be required for diagnosis. Because specific laboratory tests for some food hypersensitivities are not available, diagnosing non–IgE-mediated food allergies (eg, cow milk–induced and soy-induced enterocolitis syndromes) is more difficult than diagnosing IgE-mediated food allergies. The concentration of food-specific IgE does not correlate very well with the severity of an allergy.

For more on the workup of food allergies, read here.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.