Sickle cell disease (SCD) and its variants are genetic disorders resulting from the presence of a mutated form of hemoglobin—hemoglobin S (HbS). Globally, an estimated 300,000 individuals are born with SCD each year, the majority in sub-Saharan Africa, with about 100,000 people living with the disease in the United States. SCD most often presents in early childhood. Although the condition causes significant morbidity and mortality, morbidity, frequency of crisis, degree of anemia, and the organ systems involved vary considerably from individual to individual.
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Cite this: Emmanuel C. Besa, Sophie M. Lanzkron. Fast Five Quiz: Are You Prepared to Confront Sickle Cell Disease? - Medscape - Sep 23, 2021.