In otherwise healthy hosts, therapy does not need to cover Staphylococcus aureus, Klebsiella species, or P aeruginosa in CAP. (Most CAP regimens include Klebsiella pneumoniae coverage.) S aureus coverage should be included in patients with influenza who have focal infiltrates.
Most antibiotics used to treat CAP (eg, doxycycline, respiratory quinolones, beta lactams) are highly effective against oral anaerobes. Metronidazole and clindamycin are unnecessary unless anaerobic lung infection is suspected. For aerobic lung abscesses, clindamycin or moxifloxacin is preferable. Coverage should include the typical (Streptococcus pneumoniae, H influenzae, M catarrhalis) and atypical (Legionella and Mycoplasma species, Chlamydophila pneumoniae) pathogens.
For more on the treatment of CAP, read here.
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Cite this: Michael Stuart Bronze. Fast Five Quiz: How Much Do You Know About Pneumonia? - Medscape - Feb 16, 2016.