sacrosidase (Rx)

Brand and Other Names:Sucraid
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

oral concentrate

  • 8500 International units/mL

Congenital Sucrase-Isomaltase Deficiency (CSID)

2 mL (17,000 units) PO per meal or snack

Administration

Approximately half of the dosage should be administered at the beginning of the meal or snack; the remainder should be administered during the meal or snack

Dilute in 60-120 mL water or milk, do NOT use fruit juice

Administer cold or at room temp

Dosage Forms & Strengths

oral concentrate

  • 8500 units/mL

Congenital Sucrase-Isomaltase Deficiency (CSID)

>5 Months Old

  • <15 kg: 1 mL (8500 units) PO per meal or snack
  • >15 kg: 2 mL (17,000 units) PO per meal or snack

Administration

Approximately half of the dosage should be administered at the beginning of the meal or snack; the remainder should be administered during the meal or snack

Dilute in 60-120 mL water, milk or infant formula, do NOT use fruit juice

Administer cold or at room temp

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Interactions

Interaction Checker

and sacrosidase

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     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (1)

                  • juice (fruit)

                    juice (fruit) decreases effects of sacrosidase by Other (see comment). Minor/Significance Unknown. Comment: Reconstitution with fruit juice may decrease efficacy.

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                  Adverse Effects

                  1-10%

                  Abdominal pain

                  Constipation

                  Dehydration

                  Diarrhea

                  Headache

                  Insomnia

                  Nausea

                  Wheezing

                  Nervousnes

                  Vomiting

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                  Warnings

                  Contraindications

                  Hypersensitivity to sacrosidase, yeast, yeast products, glycerol, or papain

                  Cautions

                  Sacrosidase does not provide isomaltase, dietary starch restriction may be necessary

                  Hypersensitivity reactions including bronchospasm reported; initial dose needs to be administered where adequate medical response is available to treat an acute reaction within a few minutes; identify patients at risk by performing a skin test

                  Not evaluated for acquired disaccharidase deficiency

                  Use caution in patients with diabetes; sacrosidase enables absorption of fructose and glucose

                  Product may contain papain

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                  Pregnancy & Lactation

                  Pregnancy Category: C (not absorbed, unlikely to cause fetal harm)

                  Lactation: Not absorbed, most likely safe

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Mechanism of Action

                  Sucrase replacement: Breaks down dietary sucrose to absorbable monosaccharides, which is necessary for their absorption into the gut

                  Pharmacokinetics

                  Metabolism: Broken down in GI tract to component peptides & amino acids which are then absorbed as nutrients

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                  Images

                  No images available for this drug.
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                  Patient Handout

                  Patient Education
                  sacrosidase oral

                  NO MONOGRAPH AVAILABLE AT THIS TIME

                  USES: Consult your pharmacist.

                  HOW TO USE: Consult your pharmacist.

                  SIDE EFFECTS: Consult your pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

                  PRECAUTIONS: Consult your pharmacist.

                  DRUG INTERACTIONS: Consult your pharmacist.Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

                  OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

                  NOTES: No monograph available at this time.

                  MISSED DOSE: Consult your pharmacist.

                  STORAGE: Consult your pharmacist.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

                  Information last revised July 2016. Copyright(c) 2022 First Databank, Inc.

                  IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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                  Formulary

                  FormularyPatient Discounts

                  Adding plans allows you to compare formulary status to other drugs in the same class.

                  To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

                  Adding plans allows you to:

                  • View the formulary and any restrictions for each plan.
                  • Manage and view all your plans together – even plans in different states.
                  • Compare formulary status to other drugs in the same class.
                  • Access your plan list on any device – mobile or desktop.

                  The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

                  Tier Description
                  1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
                  2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
                  3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
                  4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                  5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                  6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                  NC NOT COVERED – Drugs that are not covered by the plan.
                  Code Definition
                  PA Prior Authorization
                  Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
                  QL Quantity Limits
                  Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
                  ST Step Therapy
                  Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
                  OR Other Restrictions
                  Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.