omaveloxolone (Pending FDA Approval)

Brand and Other Names:
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Dosing & Uses

AdultPediatric

Friedreich Ataxia

Pending FDA approval for Friedreich ataxia

Friedreich Ataxia

Pending FDA approval for Friedreich ataxia

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Pharmacology

Mechanism of Action

Activates nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that induces molecular pathways that promote resolution of inflammation by restoring mitochondrial function, reducing oxidative stress, and inhibiting proinflammatory signaling

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.