Octacosanol (Herb/Suppl)

Brand and Other Names:octacosyl alcohol
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Suggested Dosing

Exercise Endurance

1 mg PO qDay

Cholesterol Lowering

10-20 mg PO qDay

Parkinson's Disease

5 mg PO TID with meals

Amytrophic Lateral Sclerosis (ALS)

40 mg PO qDay

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Suggested Uses

Enhance physical endurance

Lower cholesterol & increase HDL

Parkinson's Disease

ALS

Efficacy

Small clinical studies suggest some benefit regarding endurance & Parkinson's Disease

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Interactions

Interaction Checker

and Octacosanol

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (72)

                  • acebutolol

                    octacosanol increases effects of acebutolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • amiloride

                    octacosanol increases effects of amiloride by pharmacodynamic synergism. Minor/Significance Unknown.

                  • amlodipine

                    octacosanol increases effects of amlodipine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • atenolol

                    octacosanol increases effects of atenolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • bendroflumethiazide

                    octacosanol increases effects of bendroflumethiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • betaxolol

                    octacosanol increases effects of betaxolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • bisoprolol

                    octacosanol increases effects of bisoprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • bosentan

                    octacosanol increases effects of bosentan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • bumetanide

                    octacosanol increases effects of bumetanide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • candesartan

                    octacosanol increases effects of candesartan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • carvedilol

                    octacosanol increases effects of carvedilol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • celiprolol

                    octacosanol increases effects of celiprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • chlorothiazide

                    octacosanol increases effects of chlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • chlorthalidone

                    octacosanol increases effects of chlorthalidone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • ciprofibrate

                    octacosanol increases effects of ciprofibrate by pharmacodynamic synergism. Minor/Significance Unknown.

                  • clevidipine

                    octacosanol increases effects of clevidipine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • clonidine

                    octacosanol increases effects of clonidine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • cyclopenthiazide

                    octacosanol increases effects of cyclopenthiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • diltiazem

                    octacosanol increases effects of diltiazem by pharmacodynamic synergism. Minor/Significance Unknown.

                  • drospirenone

                    octacosanol increases effects of drospirenone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • enalapril

                    octacosanol increases effects of enalapril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • eplerenone

                    octacosanol increases effects of eplerenone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • eprosartan

                    octacosanol increases effects of eprosartan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • esmolol

                    octacosanol increases effects of esmolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • ethacrynic acid

                    octacosanol increases effects of ethacrynic acid by pharmacodynamic synergism. Minor/Significance Unknown.

                  • felodipine

                    octacosanol increases effects of felodipine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • fenofibrate

                    octacosanol increases effects of fenofibrate by pharmacodynamic synergism. Minor/Significance Unknown.

                  • fenofibrate micronized

                    octacosanol increases effects of fenofibrate micronized by pharmacodynamic synergism. Minor/Significance Unknown.

                  • fenofibric acid

                    octacosanol increases effects of fenofibric acid by pharmacodynamic synergism. Minor/Significance Unknown.

                  • fosinopril

                    octacosanol increases effects of fosinopril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • furosemide

                    octacosanol increases effects of furosemide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • gemfibrozil

                    octacosanol increases effects of gemfibrozil by pharmacodynamic synergism. Minor/Significance Unknown.

                  • guanfacine

                    octacosanol increases effects of guanfacine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • hydrochlorothiazide

                    octacosanol increases effects of hydrochlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • iloprost

                    octacosanol increases effects of iloprost by pharmacodynamic synergism. Minor/Significance Unknown.

                  • imidapril

                    octacosanol increases effects of imidapril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • indapamide

                    octacosanol increases effects of indapamide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • irbesartan

                    octacosanol increases effects of irbesartan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • isradipine

                    octacosanol increases effects of isradipine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • ketanserin

                    octacosanol increases effects of ketanserin by pharmacodynamic synergism. Minor/Significance Unknown.

                  • labetalol

                    octacosanol increases effects of labetalol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • lisinopril

                    octacosanol increases effects of lisinopril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • losartan

                    octacosanol increases effects of losartan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • mecamylamine

                    octacosanol increases effects of mecamylamine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • methyclothiazide

                    octacosanol increases effects of methyclothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • metolazone

                    octacosanol increases effects of metolazone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • metoprolol

                    octacosanol increases effects of metoprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • metyrosine

                    octacosanol increases effects of metyrosine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • moexipril

                    octacosanol increases effects of moexipril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • moxonidine

                    octacosanol increases effects of moxonidine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • nadolol

                    octacosanol increases effects of nadolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • nebivolol

                    octacosanol increases effects of nebivolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • nicardipine

                    octacosanol increases effects of nicardipine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • nifedipine

                    octacosanol increases effects of nifedipine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • nisoldipine

                    octacosanol increases effects of nisoldipine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • olmesartan

                    octacosanol increases effects of olmesartan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • penbutolol

                    octacosanol increases effects of penbutolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • perindopril

                    octacosanol increases effects of perindopril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • pindolol

                    octacosanol increases effects of pindolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • propranolol

                    octacosanol increases effects of propranolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • quinapril

                    octacosanol increases effects of quinapril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • ramipril

                    octacosanol increases effects of ramipril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • sacubitril/valsartan

                    octacosanol increases effects of sacubitril/valsartan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • sotalol

                    octacosanol increases effects of sotalol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • spironolactone

                    octacosanol increases effects of spironolactone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • telmisartan

                    octacosanol increases effects of telmisartan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • timolol

                    octacosanol increases effects of timolol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • torsemide

                    octacosanol increases effects of torsemide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • trandolapril

                    octacosanol increases effects of trandolapril by pharmacodynamic synergism. Minor/Significance Unknown.

                  • triamterene

                    octacosanol increases effects of triamterene by pharmacodynamic synergism. Minor/Significance Unknown.

                  • valsartan

                    octacosanol increases effects of valsartan by pharmacodynamic synergism. Minor/Significance Unknown.

                  • verapamil

                    octacosanol increases effects of verapamil by pharmacodynamic synergism. Minor/Significance Unknown.

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                  Adverse Effects

                  None reported

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                  Warnings

                  None

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                  Pregnancy & Lactation

                  Pregnancy Category: N/A

                  Lactation: N/A

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Absorption: low

                  Metabolism: N/A

                  Excretion: feces, metabolites in urine

                  Mechanism of Action

                  Long chain aliphatic alcohol; may improve oxygen utilization by muscle cells, lower lactic acid accumulation during exercise

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.