linzagolix (Pending FDA Approval)

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Dosing & Uses

Uterine Fibroids

Pending FDA approval for management of heavy menstrual bleeding associated with uterine fibroids

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Pharmacology

Mechanism of Action

Gonadotropin-releasing hormone (GnRH) receptor antagonist; binds to and blocks GnRH receptors in the anterior pituitary gland

Blocking GnRH receptors decreases release of gonadotropins (ie, luteinizing hormone, follicle-stimulating hormone), thereby decreasing downstream production of estrogen and progesterone by ovaries in women

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.