Flaxseed (Herb/Suppl)

Brand and Other Names:flax, graine de lin, more...leinsamen, lini semen, linoleic acid, linseed, lint bells, linum usitatissimum
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Suggested Dosing

Seed

1 tbsp PO BID-TID

15-50 g/day

Oil

15-30 ml PO qDay

equivalent to 200 mg ALA qDay

Flour Poultice

30-50 g topically PRN

Administration

Take with adequate amount of fluid to prevent bowel obstruction

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Suggested Uses

Constipation (chronic), benign prostatic hyperplasia (oil), cancer (prevention), diabetes, diverticulitis, gastritis/enteritis, hypercholesterolemia, irritable bowel syndrome, menopausal symptoms, MI prevention (oil), skin inflammation, SLE nephritis

Efficacy

Possibly effective for diabetes, hypercholesterolemia, menopausal symptoms and SLE nephritis.

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Interactions

Interaction Checker

and Flaxseed

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (1)

                • phytoestrogens

                  phytoestrogens, flaxseed. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Both contain phytoestrogens.

                Minor (0)

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                  Adverse Effects

                  Allergic reactions, anaphylactoid rxns, diarrhea (oil), intestinal obstruction

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                  Warnings

                  Contraindications

                  Bowel obstruction, cancer (breast, ovarian, uterine), endometriosis, esophageal stricture, hormone sensitive conditions, hypertriglyceridemia, intestinal inflammation, acute, uterine fibroids

                  Cautions

                  Bleeding disorders (oil)

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                  Pregnancy & Lactation

                  Pregnancy Category: avoid use

                  Lactation: avoid use

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Metabolism: N/A

                  Excretion: N/A

                  Mechanism of Action

                  Seeds: bulk-forming laxative; prevent enterohepatic recirculation of cholesterol

                  Oil: source of alpha-linolenic acid, an essential component of cell membranes & precursor for anti-inflammatory prostaglandins

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.