vitamin D (Rx, OTC)

Brand and Other Names:Drisdol, Calciferol, more...cholecalciferol, 1,25-Dihydroxycholecalciferol, ergocalciferol
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Dosing & Uses

AdultPediatricGeriatric

Dosage Forms & Strengths

1 mcg = 40 international units (IU)

oral solution

  • 8000IU/mL (200mcg/mL)

capsule

  • 50,000IU (1.25mg)

tablet

  • 400IU (10mcg)
  • 2000IU (50mcg)

Nutritional Supplementation

Recommended daily allowance (RDA)

19-70 years: 600 IU (15 mcg)/day

Pregnant or lactating women: 600 IU (15 mcg)/day

Osteoporosis

Prophylaxis and treatment

>50 years: 800-1000 IU (20-25 mcg) PO once daily with calcium supplements

Hypoparathyroidism

50,000-200,000 IU (0.625-5 mg) PO once daily with calcium supplements

Vitamin D-Resistant Rickets

12,000-500,000 IU (0.3-12.5 mg) PO once daily

Familial Hypophosphatemia

10,000-60,000 IU (0.25-1.5 mg) PO once daily with phosphate supplements

Dosage Forms & Strengths

1 mcg = 40 IU

oral solution

  • 8000IU/mL (200mcg/mL)

capsule

  • 50,000IU (1.25mg)

tablet

  • 400IU (10mcg)
  • 2000IU (50mcg)

Nutritional Supplementation

RDA

0-12 months: 400 IU (10 mcg) PO once daily

1-18 years: 600 IU (15 mcg) PO once daily

Vitamin D-Resistant Rickets

12,000-500,000 IU (0.3-12.5 mg) PO once daily

Familial Hypophosphatemia

40,000-80,000 IU (1-2 mg) PO once daily with phosphate supplements; may be reduced after stage of growth is complete

Nutritional Supplementation

RDA

<70 years: 600 IU (15 mcg) PO once daily

>70 years: 800 IU (20 mcg) PO once daily

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Interactions

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              Serious - Use Alternative (2)

              • pexidartinib

                vitamin D and pexidartinib both increase Other (see comment). Avoid or Use Alternate Drug. Pexidartinib can cause hepatotoxicity. Avoid coadministration of pexidartinib with other products know to cause hepatoxicity.

              • pretomanid

                vitamin D, pretomanid. Either increases toxicity of the other by Other (see comment). Avoid or Use Alternate Drug. Comment: Pretomanid regimen associated with hepatotoxicity. Avoid alcohol and hepatotoxic agents, including herbal supplements and drugs other than bedaquiline and linezolid.

              Monitor Closely (25)

              • aluminum hydroxide

                vitamin D increases levels of aluminum hydroxide by Other (see comment). Use Caution/Monitor. Comment: Avoid coadministration. Chronic use of aluminum-containing antacids in conjunction with vitamin D can lead to aluminum retention and possible toxicity.

              • calcium acetate

                vitamin D, calcium acetate. Other (see comment). Use Caution/Monitor. Comment: The concurrent use of vitamin D with calcium salts is generally beneficial; in some patients this combination may result in hypercalcemia.

              • calcium carbonate

                vitamin D, calcium carbonate. Other (see comment). Use Caution/Monitor. Comment: The concurrent use of vitamin D with calcium salts is generally beneficial; in some patients this combination may result in hypercalcemia.

              • calcium chloride

                vitamin D, calcium chloride. Other (see comment). Use Caution/Monitor. Comment: The concurrent use of vitamin D with calcium salts is generally beneficial; in some patients this combination may result in hypercalcemia.

              • calcium citrate

                vitamin D, calcium citrate. Other (see comment). Use Caution/Monitor. Comment: The concurrent use of vitamin D with calcium salts is generally beneficial; in some patients this combination may result in hypercalcemia.

              • calcium gluconate

                vitamin D, calcium gluconate. Other (see comment). Use Caution/Monitor. Comment: The concurrent use of vitamin D with calcium salts is generally beneficial; in some patients this combination may result in hypercalcemia.

              • chlorothiazide

                chlorothiazide increases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Combination may increase hypercalcemic effect of vitamin D analogs. Use with caution.

              • chlorthalidone

                chlorthalidone increases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Combination may increase hypercalcemic effect of vitamin D analogs. Use with caution.

              • cholestyramine

                cholestyramine will decrease the level or effect of vitamin D by Other (see comment). Use Caution/Monitor. Bile acid sequestrants may decrease the absorption of fat-soluble vitamins. Administer vitamin supplementation at least 4 hours prior to cholestyramine.

              • colesevelam

                colesevelam will decrease the level or effect of vitamin D by Other (see comment). Use Caution/Monitor. Bile acid sequestrants may decrease the absorption of fat-soluble vitamins. Administer vitamin supplementation at least 4 hours prior to colesevelam.

              • colestipol

                colestipol will decrease the level or effect of vitamin D by Other (see comment). Use Caution/Monitor. Bile acid sequestrants may decrease the absorption of fat-soluble vitamins. Administer vitamin supplementation at least 4 hours prior to colestipol.

              • digoxin

                vitamin D increases toxicity of digoxin by Other (see comment). Use Caution/Monitor. Comment: Vitamin D may cause hypercalcemia which may affect the actions of digoxin and/or lead to cardiac arrhythmias.

              • fosphenytoin

                fosphenytoin decreases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Vitamin D supplementation or dosage adjustments may be required in patients who are receiving chronic treatment with anticonvulsants.

              • hydrochlorothiazide

                hydrochlorothiazide increases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Combination may increase hypercalcemic effect of vitamin D analogs. Use with caution.

              • indapamide

                indapamide increases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Combination may increase hypercalcemic effect of vitamin D analogs. Use with caution.

              • magnesium citrate

                vitamin D increases levels of magnesium citrate by Other (see comment). Use Caution/Monitor. Comment: Vitamin D can increase serum magnesium concentrations, particularly in the presence of renal impairment. The combined use of vitamin D and magnesium-containing products should be avoided, if possible, in patients with chronic renal failure.

              • magnesium hydroxide

                vitamin D increases levels of magnesium hydroxide by Other (see comment). Use Caution/Monitor. Comment: Vitamin D can increase serum magnesium concentrations, particularly in the presence of renal impairment. The combined use of vitamin D and magnesium-containing products should be avoided, if possible, in patients with chronic renal failure.

              • methyclothiazide

                methyclothiazide increases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Combination may increase hypercalcemic effect of vitamin D analogs. Use with caution.

              • metolazone

                metolazone increases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Combination may increase hypercalcemic effect of vitamin D analogs. Use with caution.

              • mineral oil

                mineral oil will decrease the level or effect of vitamin D by Other (see comment). Use Caution/Monitor. Avoid concomitant use of mineral oil and vitamin D supplements to avoid risk of decreased absorption of vitamin D. Applies to only oral administration of these agents.

              • orlistat

                orlistat will decrease the level or effect of vitamin D by Other (see comment). Use Caution/Monitor. When combination must be used, may consider administering vitamin D at least 2 hours before or after administration of orlistat.

              • phenobarbital

                phenobarbital decreases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Vitamin D supplementation or dosage adjustments may be required in patients who are receiving chronic treatment with anticonvulsants.

              • phenytoin

                phenytoin decreases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Vitamin D supplementation or dosage adjustments may be required in patients who are receiving chronic treatment with anticonvulsants.

              • primidone

                primidone decreases effects of vitamin D by Other (see comment). Use Caution/Monitor. Comment: Vitamin D supplementation or dosage adjustments may be required in patients who are receiving chronic treatment with anticonvulsants.

              • sucralfate

                vitamin D increases levels of sucralfate by Other (see comment). Use Caution/Monitor. Comment: Avoid coadministration. Vitamin D analogs may increase the absorption of aluminum from sucralfate. .

              Minor (0)

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                Adverse Effects

                Frequency Not Defined

                Arrhythmias

                Confusion

                Constipation

                Dry mouth

                Headache

                Hypercalcemia

                Lethargy

                Metallic taste

                Muscle or bone pain

                Nausea

                Sluggishness

                Vomiting

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                Warnings

                Contraindications

                Hypercalcemia

                Hypervitaminosis D

                Ergocalciferol (oral): Gastrointestinal (GI), liver, or biliary disease associated with malabsorption of vitamin D analogues

                Documented hypersensitivity with drugs that could have allergenic crossreactivity with ergocalceferol

                Cautions

                Ergocalciferol: Use with caution in renal impairment (strong caution), heart disease, kidney stones, arteriosclerosis

                Obtain serum calcium twice weekly during titration

                Discontinue if patient becomes hypercalcemic

                Presence of tartrazine in some products may cause allergic reactions

                Vitamin D toxicity may last ≥2 months after therapy is discontinued

                Restrict intake in infants with idiopathic hypercalcemia

                Concurrent use of cardiac glycosides

                Adequate clinical response to vitamin D therapy is dependent on adequate dietary calcium

                Maintain normal serum phosphorous concentrations in patients treated for hyperphosphatemia to prevent metastatic calcification

                When treating hypoparathyroidism, concomitant treatment with intravenous calcium, parathyroid hormone, and/or dihydrotachysterol may also be required

                Adults with a body mass index (BMI) greater than 30 kg/m² are at high risk for vitamin D deficiency due to storage of vitamin D in adipose tissue; doses higher than recommended daily allowance may be required, but must be carefully monitored to avoid toxicity

                Metabolism of vitamin D may be altered in patients with chronic kidney disease

                In renal impairment, supplementation with ergocalciferol may be necessary; monitor closely

                In patients with rickets, the range between therapeutic and toxic doses is narrow in vitamin D–resistant patients; adjust dose based on clinical response to avoid toxicity

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                Pregnancy & Lactation

                Pregnancy category: C (ergocalciferol)

                Lactation: Drug is distributed into breast milk; use with caution

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Mechanism of Action

                Stimulates calcium and phosphate absorption from small intestine; stimulates phosphate resorption at renal tubule; stimulates secretion of calcium into blood from bone

                Absorption

                Peak effect: 1 month with daily dosing

                Metabolism

                Metabolized in liver

                Elimination

                Excretion: Urine

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                Images

                BRAND FORM. UNIT PRICE PILL IMAGE
                cholecalciferol (vitamin D3) oral
                -
                250 mcg (10,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                50 mcg (2,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                1,250 mcg (50,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                1,250 mcg (50,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                50 mcg (2,000 unit) chewable tablet
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                250 mcg (10,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                250 mcg (10,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                50 mcg (2,000 unit) tablet
                cholecalciferol (vitamin D3) oral
                -
                50 mcg (2,000 unit) tablet
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                1,250 mcg (50,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) tablet
                cholecalciferol (vitamin D3) oral
                -
                25 mcg (1,000 unit) chewable tablet
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) tablet
                cholecalciferol (vitamin D3) oral
                -
                10 mcg/mL (400 unit/mL) drops
                cholecalciferol (vitamin D3) oral
                -
                10 mcg/mL (400 unit/mL) drops
                cholecalciferol (vitamin D3) oral
                -
                250 mcg (10,000 unit) tablet
                cholecalciferol (vitamin D3) oral
                -
                50 mcg (2,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                250 mcg (10,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                25 mcg (1,000 unit) tablet
                cholecalciferol (vitamin D3) oral
                -
                25 mcg (1,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                25 mcg (1,000 unit) tablet
                cholecalciferol (vitamin D3) oral
                -
                25 mcg (1,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                50 mcg (2,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                10 mcg (400 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                25 mcg (1,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                10 mcg/mL (400 unit/mL) drops
                cholecalciferol (vitamin D3) oral
                -
                125 mcg (5,000 unit) capsule
                cholecalciferol (vitamin D3) oral
                -
                25 mcg (1,000 unit) tablet
                cholecalciferol (vitamin D3) oral
                -
                50 mcg (2,000 unit) tablet
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) tablet
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) capsule
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) tablet
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) tablet
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) capsule
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) capsule
                Vitamin D3 oral
                -
                10 mcg (400 unit) capsule
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) capsule
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) chewable tablet
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) chewable tablet
                Vitamin D3 oral
                -
                10 mcg (400 unit) tablet
                Vitamin D3 oral
                -
                10 mcg (400 unit) tablet
                Vitamin D3 oral
                -
                10 mcg (400 unit) tablet
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) capsule
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) capsule
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) capsule
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) tablet
                Vitamin D3 oral
                -
                125 mcg (5,000 unit) tablet
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) tablet
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) tablet
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) chewable tablet
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) capsule
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) tablet
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) tablet
                Vitamin D3 oral
                -
                10 mcg (400 unit) tablet
                Vitamin D3 oral
                -
                25 mcg (1,000 unit) chewable tablet
                Vitamin D3 oral
                -
                50 mcg (2,000 unit) capsule
                Replesta NX oral
                -
                350 mcg (14,000 unit) wafer
                D3-2000 oral
                -
                50 mcg (2,000 unit) capsule
                Thera-D 4000 oral
                -
                100 mcg (4,000 unit) tablet
                Thera-D oral
                -
                50 mcg (2,000 unit) tablet
                Decara oral
                -
                1,250 mcg (50,000 unit) capsule
                Decara oral
                -
                1,250 mcg (50,000 unit) capsule
                Decara oral
                -
                1,250 mcg (50,000 unit) capsule
                Decara oral
                -
                625 mcg (25,000 unit) capsule
                Decara oral
                -
                625 mcg (25,000 unit) capsule
                Decara oral
                -
                250 mcg (10,000 unit) capsule
                D-Vi-Sol oral
                -
                10 mcg/mL (400 unit/mL) drops
                Replesta oral
                -
                1,250 mcg (50,000 unit) wafer
                Dialyvite Vitamin D3 Max oral
                -
                1,250 mcg (50,000 unit) tablet
                Baby's Super Daily D3 oral
                -
                10 mcg/drop (400 unit/drop) drops

                Copyright © 2010 First DataBank, Inc.

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                Patient Handout

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                Patient Education
                cholecalciferol (vitamin D3) oral

                VITAMIN D - ORAL

                COMMON BRAND NAME(S): Calciferol, Drisdol

                USES: Vitamin D (ergocalciferol-D2, cholecalciferol-D3, alfacalcidol) is a fat-soluble vitamin that helps your body absorb calcium and phosphorus. Having the right amount of vitamin D, calcium, and phosphorus is important for building and keeping strong bones. Vitamin D is used to treat and prevent bone disorders (such as rickets, osteomalacia). Vitamin D is made by the body when skin is exposed to sunlight. Sunscreen, protective clothing, limited exposure to sunlight, dark skin, and age may prevent getting enough vitamin D from the sun.Vitamin D with calcium is used to treat or prevent bone loss (osteoporosis). Vitamin D is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia). It may be used in kidney disease to keep calcium levels normal and allow normal bone growth. Vitamin D drops (or other supplements) are given to breast-fed infants because breast milk usually has low levels of vitamin D.

                HOW TO USE: Take vitamin D by mouth as directed. Vitamin D is best absorbed when taken after a meal but may be taken with or without food. Alfacalcidol is usually taken with food. Follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.If your doctor has prescribed this medication, take as directed by your doctor. Your dosage is based on your medical condition, amount of sun exposure, diet, age, and response to treatment.If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.If you are taking the chewable tablet or wafers, chew the medication thoroughly before swallowing. Do not swallow whole wafers.If you are taking the rapidly-dissolving tablets, dry your hands before handling the medication. Place each dose on the tongue, allow it to dissolve completely, and then swallow it with saliva or water. You do not need to take this medication with water.Certain medications (bile acid sequestrants such as cholestyramine/colestipol, mineral oil, orlistat) can decrease the absorption of vitamin D. Take your doses of these medications as far as possible from your doses of vitamin D (at least 2 hours apart, longer if possible). It may be easiest to take vitamin D at bedtime if you are also taking these other medications. Ask your doctor or pharmacist how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day if you are taking it once a day. If you are taking this medication only once a week, remember to take it on the same day each week. It may help to mark your calendar with a reminder.If your doctor has recommended that you follow a special diet (such as a diet high in calcium), it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.If you think you may have a serious medical problem, get medical help right away.

                SIDE EFFECTS: Vitamin D at normal doses usually has no side effects. If you have any unusual effects, contact your doctor or pharmacist promptly.If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Too much vitamin D can cause harmful high calcium levels. Tell your doctor right away if any of these signs of high vitamin D/calcium levels occur: nausea/vomiting, constipation, loss of appetite, increased thirst, increased urination, mental/mood changes, unusual tiredness.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

                PRECAUTIONS: Before taking vitamin D, tell your doctor or pharmacist if you are allergic to it; or to other vitamin D products (such as calcitriol); or if you have any other allergies. This product may contain inactive ingredients (such as peanut/soy), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: high calcium/vitamin D levels (hypercalcemia/hypervitaminosis D), difficulty absorbing nutrition from food (malabsorption syndrome), kidney disease, liver disease.Liquid products, chewable tablets, or dissolving tablets may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is advised if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).During pregnancy, doses of vitamin D greater than the recommended dietary allowance should be used only when clearly needed. Discuss the risks and benefits with your doctor.This medication passes into breast milk. Consult your doctor before breast-feeding.

                DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: burosumab, phosphate binders.Check the labels on all your prescription and nonprescription/herbal products (such as antacids, laxatives, vitamins) because they may contain calcium, magnesium, phosphate, or vitamin D. Ask your pharmacist about using those products safely.Vitamin D is very similar to calcitriol. Do not use medications containing calcitriol while using vitamin D.This medication may interfere with certain laboratory tests (including cholesterol tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

                OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: seizures, confusion, irregular heartbeat.

                NOTES: Keep all regular medical and laboratory appointments. If your doctor has prescribed this medication, laboratory and/or medical tests (such as calcium/magnesium/phosphorus levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers, and fatty fish.

                MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

                STORAGE: Store vitamin D products (except alfacalcidol) at room temperature away from light and moisture. Do not store in the bathroom. Store alfacalcidol drops in the refrigerator between 36-46 degrees F (2-8 degrees C). Do not freeze. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

                Information last revised July 2021. Copyright(c) 2021 First Databank, Inc.

                IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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                Formulary

                FormularyPatient Discounts

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                Tier Description
                1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
                2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
                3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
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                5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
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                NC NOT COVERED – Drugs that are not covered by the plan.
                Code Definition
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                QL Quantity Limits
                Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
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                Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.