boron (OTC)

Brand and Other Names:
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Dosing & Uses

AdultPediatric

Acceptable Safe Boron Intake

Natural product; no established RDA for this nutrient

1-20 mg/day; maximum tolerable intake ~20 mg/day

Acceptable Safe Boron Intake

1-3 years: 3 mg/day

3-8 years: 6 mg/day

8-13 years: 11 mg/day

13-18 years: 17 mg/day

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Interactions

Interaction Checker

and boron

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (8)

                  • bazedoxifene/conjugated estrogens

                    boron increases levels of bazedoxifene/conjugated estrogens by altering metabolism. Minor/Significance Unknown.

                  • conjugated estrogens

                    boron increases levels of conjugated estrogens by altering metabolism. Minor/Significance Unknown.

                  • conjugated estrogens, vaginal

                    boron increases levels of conjugated estrogens, vaginal by altering metabolism. Minor/Significance Unknown.

                  • estradiol

                    boron increases levels of estradiol by altering metabolism. Minor/Significance Unknown.

                  • estrogens conjugated synthetic

                    boron increases levels of estrogens conjugated synthetic by altering metabolism. Minor/Significance Unknown.

                  • estrogens esterified

                    boron increases levels of estrogens esterified by altering metabolism. Minor/Significance Unknown.

                  • estropipate

                    boron increases levels of estropipate by altering metabolism. Minor/Significance Unknown.

                  • mestranol

                    boron increases levels of mestranol by altering metabolism. Minor/Significance Unknown.

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                  Adverse Effects

                  Frequency Not Defined

                  Blue/green discoloration of feces

                  Dermatitis

                  Diarrhea

                  Epigastric pain

                  Nausea

                  Renal impairment (rare: high dose)

                  Vomiting

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                  Warnings

                  Contraindications

                  None reported

                  Cautions

                  Not yet fully established as required for human nutrition

                  There is no evidence that boron supplementation higher than levels found in diet is beneficial

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                  Pregnancy & Lactation

                  Pregnancy Category: Safe when used below epected levels; not for intravaginal use as it has been associated with birth defects

                  Lactation: Not studied

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Mechanism of Action

                  Has role in mineral metabolism & membrane function; may increase 17-ß-estradiol levels

                  Supplementation useful when dietary intake is inadequate

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                  Images

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                  Patient Handout

                  A Patient Handout is not currently available for this monograph.
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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.