Panax Ginseng (Herb/Suppl)

Brand and Other Names:Asian Ginseng, Chinese Ginseng, more...ginseng radix, Ginseng Root, Japanese Ginseng, Jintsam, Korean Ginseng, Ninjin, Radix Ginseng, Red Ginseng, Ren Shen
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Suggested Dosing

Cut or Powdered Root

0.6-3 g PO qDay-TID

Brewed Root Tea

3 g PO qDay-TID

Erectile Dysfunction

900 mg PO TID

Topically cream applied 1 hour prior to intercouse and washed off before intercourse has been used

Diabetes

200 mg PO qDay

Other Information

100-300 mg extract TID for 3-4 weeks

Extract standardized to 7% ginsenosides

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Suggested Uses

Adaptogen: adapt to internal/external stressors, fight fatigue, increase stamina

Anxiety, athletic/physical stamina enhancement, cognitive function, enhancement, depression, fertility (male), headaches, immunostimulant, menopausal hot-flashes, impotence

Efficacy

Possibly effective in cognitive function, diabetes, erectile dysfunction and premature ejaculation

Possibly ineffective for athletic performance, menopausal symptoms and quality of life

Insufficient reliable evidence to rate breast cancer, bronchitis, cancer, common cold, congestive heart failure and influenza

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Interactions

Interaction Checker

and Panax Ginseng

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (69)

                • aceclofenac

                  aceclofenac and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • acemetacin

                  acemetacin and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • agrimony

                  agrimony and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • alfalfa

                  alfalfa and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • alteplase

                  alteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • American ginseng

                  American ginseng and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • antithrombin alfa

                  antithrombin alfa and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • antithrombin III

                  antithrombin III and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • argatroban

                  argatroban and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • aspirin

                  aspirin and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • aspirin rectal

                  aspirin rectal and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • aspirin/citric acid/sodium bicarbonate

                  aspirin/citric acid/sodium bicarbonate and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • bemiparin

                  bemiparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • bivalirudin

                  bivalirudin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • celecoxib

                  celecoxib and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • cinnamon

                  cinnamon and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • cordyceps

                  cordyceps and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • dabigatran

                  dabigatran and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • dalteparin

                  dalteparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • diclofenac

                  diclofenac and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • diflunisal

                  diflunisal and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • dong quai

                  dong quai and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • enoxaparin

                  enoxaparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • epoprostenol

                  epoprostenol and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • etodolac

                  etodolac and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • fennel

                  fennel and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • fenoprofen

                  fenoprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • feverfew

                  feverfew and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • flurbiprofen

                  flurbiprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • fondaparinux

                  fondaparinux and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • forskolin

                  forskolin and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • garlic

                  garlic and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • ginger

                  ginger and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • ginkgo biloba

                  ginkgo biloba and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • heparin

                  heparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • horse chestnut seed

                  horse chestnut seed and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • ibuprofen

                  ibuprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • ibuprofen IV

                  ibuprofen IV and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • indomethacin

                  indomethacin and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • ketoprofen

                  ketoprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • ketorolac

                  ketorolac and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • ketorolac intranasal

                  ketorolac intranasal and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • lornoxicam

                  lornoxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • meclofenamate

                  meclofenamate and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • mefenamic acid

                  mefenamic acid and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • meloxicam

                  meloxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • mistletoe

                  panax ginseng increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • nabumetone

                  nabumetone and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • naproxen

                  naproxen and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • nettle

                  panax ginseng increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • oxaprozin

                  oxaprozin and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • parecoxib

                  parecoxib and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • pau d'arco

                  panax ginseng and pau d'arco both increase anticoagulation. Use Caution/Monitor.

                • phenindione

                  phenindione and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • phytoestrogens

                  panax ginseng and phytoestrogens both increase anticoagulation. Use Caution/Monitor.

                • piroxicam

                  piroxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • protamine

                  protamine and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • reishi

                  panax ginseng and reishi both increase anticoagulation. Use Caution/Monitor.

                • reteplase

                  reteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • salicylates (non-asa)

                  salicylates (non-asa) and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • salsalate

                  salsalate and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • Siberian ginseng

                  panax ginseng and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.

                • sulfasalazine

                  sulfasalazine and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • sulindac

                  sulindac and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • tenecteplase

                  tenecteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • tolfenamic acid

                  tolfenamic acid and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • tolmetin

                  tolmetin and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • vitamin K1 (phytonadione)

                  panax ginseng increases and vitamin K1 (phytonadione) decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • warfarin

                  warfarin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                Minor (37)

                • amitriptyline

                  panax ginseng increases effects of amitriptyline by pharmacodynamic synergism. Minor/Significance Unknown.

                • amoxapine

                  panax ginseng increases effects of amoxapine by pharmacodynamic synergism. Minor/Significance Unknown.

                • anamu

                  anamu and panax ginseng both increase anticoagulation. Minor/Significance Unknown.

                • clomipramine

                  panax ginseng increases effects of clomipramine by pharmacodynamic synergism. Minor/Significance Unknown.

                • danshen

                  danshen and panax ginseng both increase anticoagulation. Minor/Significance Unknown.

                • desipramine

                  panax ginseng increases effects of desipramine by pharmacodynamic synergism. Minor/Significance Unknown.

                • devil's claw

                  devil's claw and panax ginseng both increase anticoagulation. Minor/Significance Unknown.

                • dosulepin

                  panax ginseng increases effects of dosulepin by pharmacodynamic synergism. Minor/Significance Unknown.

                • doxepin

                  panax ginseng increases effects of doxepin by pharmacodynamic synergism. Minor/Significance Unknown.

                • duloxetine

                  panax ginseng increases effects of duloxetine by pharmacodynamic synergism. Minor/Significance Unknown.

                • escitalopram

                  panax ginseng increases effects of escitalopram by pharmacodynamic synergism. Minor/Significance Unknown.

                • fluoxetine

                  panax ginseng increases effects of fluoxetine by pharmacodynamic synergism. Minor/Significance Unknown.

                • green tea

                  green tea, panax ginseng. Other (see comment). Minor/Significance Unknown. Comment: Use caution when combining green tea with herbs that exhibit antiplatelet effects or anticoagulant activity.

                • imipramine

                  panax ginseng increases effects of imipramine by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin aspart

                  panax ginseng increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin detemir

                  panax ginseng increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin glargine

                  panax ginseng increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin glulisine

                  panax ginseng increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin lispro

                  panax ginseng increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin NPH

                  panax ginseng increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin regular human

                  panax ginseng increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.

                • isocarboxazid

                  panax ginseng increases effects of isocarboxazid by pharmacodynamic synergism. Minor/Significance Unknown.

                • linezolid

                  panax ginseng increases effects of linezolid by pharmacodynamic synergism. Minor/Significance Unknown.

                • lofepramine

                  panax ginseng increases effects of lofepramine by pharmacodynamic synergism. Minor/Significance Unknown.

                • maprotiline

                  panax ginseng increases effects of maprotiline by pharmacodynamic synergism. Minor/Significance Unknown.

                • milnacipran

                  panax ginseng increases effects of milnacipran by pharmacodynamic synergism. Minor/Significance Unknown.

                • nefazodone

                  panax ginseng increases effects of nefazodone by pharmacodynamic synergism. Minor/Significance Unknown.

                • nortriptyline

                  panax ginseng increases effects of nortriptyline by pharmacodynamic synergism. Minor/Significance Unknown.

                • paroxetine

                  panax ginseng increases effects of paroxetine by pharmacodynamic synergism. Minor/Significance Unknown.

                • phenelzine

                  panax ginseng increases effects of phenelzine by pharmacodynamic synergism. Minor/Significance Unknown.

                • procarbazine

                  panax ginseng increases effects of procarbazine by pharmacodynamic synergism. Minor/Significance Unknown.

                • protriptyline

                  panax ginseng increases effects of protriptyline by pharmacodynamic synergism. Minor/Significance Unknown.

                • sertraline

                  panax ginseng increases effects of sertraline by pharmacodynamic synergism. Minor/Significance Unknown.

                • tranylcypromine

                  panax ginseng increases effects of tranylcypromine by pharmacodynamic synergism. Minor/Significance Unknown.

                • trazodone

                  panax ginseng increases effects of trazodone by pharmacodynamic synergism. Minor/Significance Unknown.

                • trimipramine

                  panax ginseng increases effects of trimipramine by pharmacodynamic synergism. Minor/Significance Unknown.

                • venlafaxine

                  panax ginseng increases effects of venlafaxine by pharmacodynamic synergism. Minor/Significance Unknown.

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                Adverse Effects

                Frequency Not Defined

                Allergic skin reactions

                Amenorrhea

                Appetite decreased

                Cerebral arteritis

                Cholestatic hepatitis

                Diarrhea

                Edema

                Euphoria

                Headache

                Hyperpyrexia

                Hypertension

                Hypotension

                Insomnia

                Mania

                Mastalgia

                Neonatal death

                Palpitations

                Pruritis

                Rose spots

                Stevens-Johnson syndrome

                Tachycardia

                Vaginal bleeding

                Vertigo

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                Warnings

                Contraindications

                Bleeding disorders, breast cancer, endometrial cancer, endometriosis, estrogen-dependent malignancies, diabetes, hormone sensitive conditions, hypertension, hypersensitivity, neonates, organ transplant recipients, ovarian cancer, pregnancy, thromboembolic disorders, uterine fibroids

                Cautions

                Cardiovascular disease, concurrent CYP2D6 substrates, diabetes mellitus, insomnia, peds, schizophrenia

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                Pregnancy & Lactation

                Pregnancy Category: X

                Lactation: N/A

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Mechanism of Action

                Ginsenosides have many different effects, and varying concentrations

                Some ADRs caused by contaminants

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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.