Dong Quai (Herb/Suppl)

Brand and Other Names:Angelica atropurpurea, Angelica dahurica, more...angelica sinensis, Chinese angelica, dang gui, ligustilides, Radix Angelicae Sinensis, tang-kuei
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Suggested Dosing

Extract

1 ml PO TID, OR

Other Information

1-2 g steeped in boiling water TID

Menopausal symptoms: 4.5 g powder PO qD

3-4 g PO div TID with meals, OR

520-1560 mg PO TID, OR

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Suggested Uses

Stimulate normal menstrual flow, prevent cramping

Anemia, constipation, dysmenorrhea, hypertension, psoriasis, rheumatism, skin depigmentation, ulcers

Efficacy

Controversial; apparently more effective in combination with other herbs

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Interactions

Interaction Checker

and Dong Quai

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (3)

              • aminolevulinic acid oral

                aminolevulinic acid oral, dong quai. Either increases toxicity of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Avoid administering other phototoxic drugs with aminolevulinic acid oral for 24 hr during perioperative period.

              • aminolevulinic acid topical

                dong quai, aminolevulinic acid topical. Either increases toxicity of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Each drug may increase the photosensitizing effect of the other.

              • methyl aminolevulinate

                dong quai, methyl aminolevulinate. Either increases toxicity of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Each drug may increase the photosensitizing effect of the other.

              Monitor Closely (69)

              • aceclofenac

                aceclofenac and dong quai both increase anticoagulation. Use Caution/Monitor.

              • acemetacin

                acemetacin and dong quai both increase anticoagulation. Use Caution/Monitor.

              • agrimony

                agrimony and dong quai both increase anticoagulation. Use Caution/Monitor.

              • alfalfa

                alfalfa and dong quai both increase anticoagulation. Use Caution/Monitor.

              • alteplase

                alteplase and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • American ginseng

                American ginseng and dong quai both increase anticoagulation. Use Caution/Monitor.

              • antithrombin alfa

                antithrombin alfa and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • antithrombin III

                antithrombin III and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • argatroban

                argatroban and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • aspirin

                aspirin and dong quai both increase anticoagulation. Use Caution/Monitor.

              • aspirin rectal

                aspirin rectal and dong quai both increase anticoagulation. Use Caution/Monitor.

              • aspirin/citric acid/sodium bicarbonate

                aspirin/citric acid/sodium bicarbonate and dong quai both increase anticoagulation. Use Caution/Monitor.

              • bemiparin

                bemiparin and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • bivalirudin

                bivalirudin and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • celecoxib

                celecoxib and dong quai both increase anticoagulation. Use Caution/Monitor.

              • choline magnesium trisalicylate

                choline magnesium trisalicylate and dong quai both increase anticoagulation. Use Caution/Monitor.

              • cinnamon

                cinnamon and dong quai both increase anticoagulation. Use Caution/Monitor.

              • cordyceps

                cordyceps and dong quai both increase anticoagulation. Use Caution/Monitor.

              • dabigatran

                dabigatran and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • dalteparin

                dalteparin and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • diclofenac

                diclofenac and dong quai both increase anticoagulation. Use Caution/Monitor.

              • diflunisal

                diflunisal and dong quai both increase anticoagulation. Use Caution/Monitor.

              • enoxaparin

                enoxaparin and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • epoprostenol

                dong quai and epoprostenol both increase anticoagulation. Use Caution/Monitor.

              • etodolac

                etodolac and dong quai both increase anticoagulation. Use Caution/Monitor.

              • fennel

                dong quai and fennel both increase anticoagulation. Use Caution/Monitor.

              • fenoprofen

                fenoprofen and dong quai both increase anticoagulation. Use Caution/Monitor.

              • feverfew

                dong quai and feverfew both increase anticoagulation. Use Caution/Monitor.

              • flurbiprofen

                flurbiprofen and dong quai both increase anticoagulation. Use Caution/Monitor.

              • fondaparinux

                fondaparinux and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • forskolin

                dong quai and forskolin both increase anticoagulation. Use Caution/Monitor.

              • garlic

                dong quai and garlic both increase anticoagulation. Use Caution/Monitor.

              • ginger

                dong quai and ginger both increase anticoagulation. Use Caution/Monitor.

              • ginkgo biloba

                dong quai and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.

              • heparin

                heparin and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • horse chestnut seed

                dong quai and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.

              • ibuprofen

                ibuprofen and dong quai both increase anticoagulation. Use Caution/Monitor.

              • ibuprofen IV

                ibuprofen IV and dong quai both increase anticoagulation. Use Caution/Monitor.

              • indomethacin

                indomethacin and dong quai both increase anticoagulation. Use Caution/Monitor.

              • ketoprofen

                ketoprofen and dong quai both increase anticoagulation. Use Caution/Monitor.

              • ketorolac

                ketorolac and dong quai both increase anticoagulation. Use Caution/Monitor.

              • ketorolac intranasal

                ketorolac intranasal and dong quai both increase anticoagulation. Use Caution/Monitor.

              • lornoxicam

                lornoxicam and dong quai both increase anticoagulation. Use Caution/Monitor.

              • meclofenamate

                meclofenamate and dong quai both increase anticoagulation. Use Caution/Monitor.

              • mefenamic acid

                mefenamic acid and dong quai both increase anticoagulation. Use Caution/Monitor.

              • meloxicam

                meloxicam and dong quai both increase anticoagulation. Use Caution/Monitor.

              • mistletoe

                dong quai increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • nabumetone

                nabumetone and dong quai both increase anticoagulation. Use Caution/Monitor.

              • naproxen

                naproxen and dong quai both increase anticoagulation. Use Caution/Monitor.

              • nettle

                dong quai increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • oxaprozin

                oxaprozin and dong quai both increase anticoagulation. Use Caution/Monitor.

              • panax ginseng

                dong quai and panax ginseng both increase anticoagulation. Use Caution/Monitor.

              • parecoxib

                parecoxib and dong quai both increase anticoagulation. Use Caution/Monitor.

              • pau d'arco

                dong quai and pau d'arco both increase anticoagulation. Use Caution/Monitor.

              • phenindione

                phenindione and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • phytoestrogens

                dong quai and phytoestrogens both increase anticoagulation. Use Caution/Monitor.

              • piroxicam

                piroxicam and dong quai both increase anticoagulation. Use Caution/Monitor.

              • protamine

                protamine and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • reishi

                dong quai and reishi both increase anticoagulation. Use Caution/Monitor.

              • reteplase

                reteplase and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • salicylates (non-asa)

                salicylates (non-asa) and dong quai both increase anticoagulation. Use Caution/Monitor.

              • salsalate

                salsalate and dong quai both increase anticoagulation. Use Caution/Monitor.

              • Siberian ginseng

                dong quai and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.

              • sulfasalazine

                sulfasalazine and dong quai both increase anticoagulation. Use Caution/Monitor.

              • sulindac

                sulindac and dong quai both increase anticoagulation. Use Caution/Monitor.

              • tenecteplase

                tenecteplase and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              • tolfenamic acid

                tolfenamic acid and dong quai both increase anticoagulation. Use Caution/Monitor.

              • tolmetin

                tolmetin and dong quai both increase anticoagulation. Use Caution/Monitor.

              • warfarin

                warfarin and dong quai both increase anticoagulation. Modify Therapy/Monitor Closely.

              Minor (4)

              • anamu

                anamu and dong quai both increase anticoagulation. Minor/Significance Unknown.

              • danshen

                danshen and dong quai both increase anticoagulation. Minor/Significance Unknown.

              • devil's claw

                devil's claw and dong quai both increase anticoagulation. Minor/Significance Unknown.

              • green tea

                green tea, dong quai. Other (see comment). Minor/Significance Unknown. Comment: Use caution when combining green tea with herbs that exhibit antiplatelet effects or anticoagulant activity.

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              Adverse Effects

              Frequency Not Defined

              Photodermatitis (especially A. archangelica)

              Safrole, in essential oil, is carcinogen

              Photosensitivity

              Potential mutagen

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              Warnings

              Contraindications

              Breast cancer, endometriosis, hormone sensitive conditions, ovarian cancer, uterine cancer, uterine fibroids

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              Pregnancy & Lactation

              Pregnancy Category: avoid use

              Lactation: avoid use

              Pregnancy Categories

              A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

              B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

              C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

              D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

              X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

              NA: Information not available.

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              Pharmacology

              Metabolism: N/A

              Excretion: N/A

              Mechanism of Action

              Phytoestrogen modulate endogenous estrogen effects; also contains coumarins

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              Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.